› 4qlo

X-ray diffraction
2.45Å resolution

Crystal Structure of homoserine o-acetyltransferase from Staphylococcus aureus

Released:
DOI: 10.2210/pdb4qlo/pdb
PDB entry 4qlo coloured by chain, front view.
PDB entry 4qlo coloured by chain, side view.
PDB entry 4qlo coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
Primary publication:
Structure of homoserine O-acetyltransferase from Staphylococcus aureus: the first Gram-positive ortholog structure.
Thangavelu B, Pavlovsky AG, Viola R
Acta Crystallogr F Struct Biol Commun 70 1340-5 (2014)
PMID: 25286936

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-165106 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
homoserine O-acetyltransferase Chain: A
Molecule details ›
Chain: A
Length: 360 amino acids
Theoretical weight: 41.24 KDa
Source organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
Expression system: Escherichia coli BL21
Structure domains: alpha/beta hydrolase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P6122
Unit cell:
a: 49.155Å b: 49.155Å c: 481.417Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.242 0.24 0.291
Expression system: Escherichia coli BL21

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Citations

1 review citation

Insight into de-regulation of amino acid feedback inhibition: a focus on structure analysis method.
Naz et al. (2023)
5 other articles

5 mentions without citation

Catalytic and structural properties of pheophytinase, the phytol esterase involved in chlorophyll breakdown.
Guyer et al. (2018)
4 more