› 4qpn

X-ray diffraction
1.25Å resolution

Crystal Structure of Human Methyltransferase-Like Protein 21B

Released:
DOI: 10.2210/pdb4qpn/pdb
PDB entry 4qpn coloured by chain, front view.
PDB entry 4qpn coloured by chain, side view.
PDB entry 4qpn coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tempel W, Hong BS, Seitova A, He H, Li Y, Graslund S, Arrowsmith CH, Edwards AM, Brown PJ, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188366 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EEF1A lysine methyltransferase 3 Chain: A
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 24.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q96AZ1 (Residues: 1-226; Coverage: 100%)
Gene names: EEF1AKMT3, FAM119B, HCA557A, METTL21B
Sequence domains: Lysine methyltransferase
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments

3 bound ligands:
Ligand SAH 1 x SAH
Ligand SO4 2 x SO4
Ligand UNX 14 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P61
Unit cell:
a: 38.665Å b: 38.665Å c: 193.915Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.124 0.122 0.167
Expression system: Spodoptera frugiperda

Quick links