› 4qpy

X-ray diffraction
2.38Å resolution

Crystal structure of C1QL2

Released:
DOI: 10.2210/pdb4qpy/pdb
PDB entry 4qpy coloured by chain, front view.
PDB entry 4qpy coloured by chain, side view.
PDB entry 4qpy coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structures of C1q-like proteins reveal unique features among the C1q/TNF superfamily.
Ressl S, Vu BK, Vivona S, Martinelli DC, Südhof TC, Brunger AT
Structure 23 688-99 (2015)
PMID: 25752542

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183957 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement C1q-like protein 2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 136 amino acids
Theoretical weight: 14.94 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8CFR0 (Residues: 152-287; Coverage: 51%)
Gene names: C1ql2, C1qtnf10, Ctrp10
Sequence domains: C1q domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: F432
Unit cell:
a: 225.62Å b: 225.62Å c: 225.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.17 0.216
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.
Südhof TC. (2017)
8 more

1 mention without citation

Network Pharmacology and Molecular Docking Analysis Exploring the Mechanism of Tripterygium wilfordii in the Treatment of Oral Lichen Planus.
Huang et al. (2023)