› 4qu6

X-ray diffraction
1.75Å resolution

Crystal structure of a G-rich RNA sequence binding factor 1 (GRSF1) from Homo sapiens at 1.75 A resolution

Released:
DOI: 10.2210/pdb4qu6/pdb
PDB entry 4qu6 coloured by chain, front view.
PDB entry 4qu6 coloured by chain, side view.
PDB entry 4qu6 coloured by chain, top view.
Source organisms:
Entry authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-171412 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
G-rich sequence factor 1 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12849 (Residues: 140-245; Coverage: 22%)
Gene name: GRSF1
Structure domains: Alpha-Beta Plaits
RNA 5'-(*AP*GP*GP*GP*UP*GP)-3' Chain: B
Molecule details ›
Chain: B
Length: 6 nucleotides
Theoretical weight: 1.97 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand CL 3 x CL
Ligand CA 1 x CA
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P42212
Unit cell:
a: 60.48Å b: 60.48Å c: 59.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.183 0.246
Expression systems:
  • Escherichia coli
  • Not provided

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