› 4qu7

X-ray diffraction
2.5Å resolution

Crystal structure of a G-rich RNA sequence binding factor 1 (GRSF1) from Homo sapiens at 2.50 A resolution

Released:
DOI: 10.2210/pdb4qu7/pdb
PDB entry 4qu7 coloured by chain, front view.
PDB entry 4qu7 coloured by chain, side view.
PDB entry 4qu7 coloured by chain, top view.
Source organisms:
Entry authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-171413 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
G-rich sequence factor 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 81 amino acids
Theoretical weight: 9.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12849 (Residues: 400-480; Coverage: 17%)
Gene name: GRSF1
Structure domains: Alpha-Beta Plaits
RNA 5'-(*AP*GP*GP*GP*AP*UP)-3' Chains: U, V, X
Molecule details ›
Chains: U, V, X
Length: 6 nucleotides
Theoretical weight: 1.96 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P212121
Unit cell:
a: 52.54Å b: 72.32Å c: 103.84Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.192 0.254
Expression systems:
  • Escherichia coli
  • Not provided

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