› 4quz

X-ray diffraction
2.35Å resolution

Crystal structure of Feline Norovirus P Domain

Released:
DOI: 10.2210/pdb4quz/pdb
PDB entry 4quz coloured by chain, front view.
PDB entry 4quz coloured by chain, side view.
PDB entry 4quz coloured by chain, top view.
Source organism: Norovirus cat/GIV.2/CU081210E/USA/2010
Primary publication:
Structural analysis of a feline norovirus protruding domain.
Singh BK, Glatt S, Ferrer JL, Koromyslova AD, Leuthold MM, Dunder J, Hansman GS
Virology 474 181-5 (2015)
PMID: 25463616

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 341 amino acids
Theoretical weight: 36.66 KDa
Source organism: Norovirus cat/GIV.2/CU081210E/USA/2010
Expression system: Escherichia coli
UniProt:
  • Canonical: H8YRY9 (Residues: 225-565; Coverage: 59%)
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P21
Unit cell:
a: 57.74Å b: 99.92Å c: 59.61Å
α: 90° β: 97.92° γ: 90°
R-values:
R R work R free
0.217 0.214 0.268
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Emergence of norovirus strains: A tale of two genes.
Parra GI. (2019)
4 other articles

1 mention without citation

Genomics Analyses of GIV and GVI Noroviruses Reveal the Distinct Clustering of Human and Animal Viruses.
Ford-Siltz et al. (2019)