› 4r0b

X-ray diffraction
2.45Å resolution

Structure of dimeric human glycodelin

Released:
DOI: 10.2210/pdb4r0b/pdb
PDB entry 4r0b coloured by chain, front view.
PDB entry 4r0b coloured by chain, side view.
PDB entry 4r0b coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans.
Schiefner A, Rodewald F, Neumaier I, Skerra A
Biochem J 466 95-104 (2015)
PMID: 25422905

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140661 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycodelin Chain: A
Molecule details ›
Chain: A
Length: 169 amino acids
Theoretical weight: 19.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09466 (Residues: 20-180; Coverage: 99%)
Gene name: PAEP
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P6122
Unit cell:
a: 57.003Å b: 57.003Å c: 198.641Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.2 0.257
Expression system: Escherichia coli

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Citations

4 review citations

The Pleiotropic Effect of Glycodelin-A in Early Pregnancy.
Lee et al. (2016)
3 more