› 4rgd

X-ray diffraction
1.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175270 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide antibiotic AS-48 Chains: A, B
Molecule details ›
Chains: A, B
Length: 70 amino acids
Theoretical weight: 7.27 KDa
Source organism: Enterococcus faecalis
Expression system: Enterococcus faecalis
UniProt:
  • Canonical: Q47765 (Residues: 36-105; Coverage: 67%)
Gene names: as-48, as48A, bacA
Sequence domains: Bacteriocin class IId cyclical uberolysin-like
Structure domains: Bacteriocin AS-48

Ligands and Environments

1 bound ligand:
Ligand CIT 1 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 32.82Å b: 49.91Å c: 41.72Å
α: 90° β: 98.16° γ: 90°
R-values:
R R work R free
0.12 0.118 0.147
Expression system: Enterococcus faecalis

Quick links

Citations

6 review citations

Bacteriocins of lactic acid bacteria: extending the family.
Alvarez-Sieiro et al. (2016)
5 more

1 mention without citation

State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective.
Tuder et al. (2006)