› 4rlb

X-ray diffraction
2.7Å resolution

Crystal structure of Acinetobacter baumannii CarO2

Released:
DOI: 10.2210/pdb4rlb/pdb
PDB entry 4rlb coloured by chain, front view.
PDB entry 4rlb coloured by chain, side view.
PDB entry 4rlb coloured by chain, top view.
Source organism: Acinetobacter baumannii
Primary publication:
Small-Molecule Transport by CarO, an Abundant Eight-Stranded β-Barrel Outer Membrane Protein from Acinetobacter baumannii.
Zahn M, D'Agostino T, Eren E, Baslé A, Ceccarelli M, van den Berg B
J Mol Biol 427 2329-39 (2015)
PMID: 25846137

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176972 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbapenem-associated resistance protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 27.62 KDa
Source organism: Acinetobacter baumannii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5DL42 (Residues: 22-247; Coverage: 100%)
Gene name: carO
Structure domains: Porin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P6522
Unit cell:
a: 139.602Å b: 139.602Å c: 138.759Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.192 0.19 0.228
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Acinetobacter baumannii Antibiotic Resistance Mechanisms.
Kyriakidis et al. (2021)
5 more

3 mentions without citation

Mutation of CarO participates in drug resistance in imipenem-resistant Acinetobacter baumannii.
Zhu et al. (2019)
2 more