› 4rlv

X-ray diffraction
3.49Å resolution

Crystal Structure of AnkB 24 Ankyrin Repeats in Complex with AnkR Autoinhibition Segment

Released:
DOI: 10.2210/pdb4rlv/pdb
PDB entry 4rlv coloured by chain, front view.
PDB entry 4rlv coloured by chain, side view.
PDB entry 4rlv coloured by chain, top view.
Source organisms:
Primary publication:
Structural basis of diverse membrane target recognitions by ankyrins.
Wang C, Wei Z, Chen K, Ye F, Yu C, Bennett V, Zhang M
Elife 3 (2014)
PMID: 25383926

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ankyrin-1; Ankyrin-2 Chain: A
Molecule details ›
Chain: A
Length: 910 amino acids
Theoretical weight: 98.01 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: Q02357 (Residues: 5-5; Coverage: 0%)
  • Canonical: Q01484 (Residues: 29-873; Coverage: 21%)
Gene names: ANK2, ANKB, Ank-1, Ank1
Sequence domains: Ankyrin repeat

Ligands and Environments

1 bound ligand:
Ligand SO4 9 x SO4
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: R32
Unit cell:
a: 179.685Å b: 179.685Å c: 304.856Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.222 0.22 0.253
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Cytoskeletal control of axon domain assembly and function.
Zhang et al. (2016)
6 more

10 mentions without citation

Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Jin et al. (2017)
9 more