› 4rne

X-ray diffraction
1.01Å resolution

Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions

Released:
DOI: 10.2210/pdb4rne/pdb
PDB entry 4rne coloured by chain, front view.
PDB entry 4rne coloured by chain, side view.
PDB entry 4rne coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
Fyfe AC, Dunten PW, Martick MM, Scott WG
J Mol Biol 427 2205-19 (2015)
PMID: 25861762

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196873 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(*UP*GP*GP*GP*GP*U)-3') Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 6 nucleotides
Theoretical weight: 1.95 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand SR 7 x SR
Ligand NA 4 x NA
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: C2221
Unit cell:
a: 37.656Å b: 54.197Å c: 95.677Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.103 0.102 0.119
Expression system: Not provided

Quick links

Citations

4 citation in other articles

Unraveling the structural basis for the exceptional stability of RNA G-quadruplexes capped by a uridine tetrad at the 3' terminus.
Andrałojć et al. (2019)
3 more

5 mentions without citation

Non-G Base Tetrads.
Escaja et al. (2022)
4 more