› 4rpb

X-ray diffraction
1.61Å resolution

Crystal Structure of P Domain of Snow Mountain Norovirus

Released:
DOI: 10.2210/pdb4rpb/pdb
PDB entry 4rpb coloured by chain, front view.
PDB entry 4rpb coloured by chain, side view.
PDB entry 4rpb coloured by chain, top view.
Source organism: Norovirus Hu/GII.2/KL109/1978/MYS
Primary publication:
Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens.
Singh BK, Leuthold MM, Hansman GS
mSphere 1
PMID: 27303720

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125630 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 310 amino acids
Theoretical weight: 34.01 KDa
Source organism: Norovirus Hu/GII.2/KL109/1978/MYS
Expression system: Escherichia coli
UniProt:
  • Canonical: K7X601 (Residues: 225-532; Coverage: 57%)
Gene name: VP1
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 7 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 166.64Å b: 96.17Å c: 64.12Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.182
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides.
Schroten et al. (2016)
2 more

5 mentions without citation

Genetic Analysis of Human Norovirus Strains in Japan in 2016-2017.
Nagasawa et al. (2018)
4 more