› 4rqa

X-ray diffraction
1.48Å resolution

Crystal Structure of a Hypoxanthine Phosphoribosyltransferase (target ID NYSGRC-029686) from Staphylococcus aureus (orthorhombic space group)

Released:
DOI: 10.2210/pdb4rqa/pdb
PDB entry 4rqa coloured by chain, front view.
PDB entry 4rqa coloured by chain, side view.
PDB entry 4rqa coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
Entry authors: Ghosh A, Almo SC, New York Structural Genomics Research Consortium (NYSGRC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-165164 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hypoxanthine phosphoribosyltransferase Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 21.24 KDa
Source organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
Expression system: Escherichia coli BL21(DE3)
Structure domains: Rossmann fold

Ligands and Environments

4 bound ligands:
Ligand GOL 2 x GOL
Ligand NA 1 x NA
Ligand ACT 1 x ACT
Ligand CL 3 x CL
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: I222
Unit cell:
a: 66.158Å b: 71.919Å c: 103.036Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.152 0.15 0.194
Expression system: Escherichia coli BL21(DE3)

Quick links