› 4rqb

X-ray diffraction
2.45Å resolution

Crystal Structure of a Hypoxanthine Phosphoribosyltransferase (target ID NYSGRC-029686) from Staphylococcus aureus (tetragonal space group)

Released:
DOI: 10.2210/pdb4rqb/pdb
PDB entry 4rqb coloured by chain, front view.
PDB entry 4rqb coloured by chain, side view.
PDB entry 4rqb coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
Entry authors: Ghosh A, Almo SC, New York Structural Genomics Research Consortium (NYSGRC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-165166 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hypoxanthine phosphoribosyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 186 amino acids
Theoretical weight: 21.24 KDa
Source organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
Expression system: Escherichia coli BL21(DE3)
Structure domains: Rossmann fold

Ligands and Environments

4 bound ligands:
Ligand SO4 4 x SO4
Ligand UNL 2 x UNL
Ligand GOL 3 x GOL
Ligand CL 1 x CL
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P41212
Unit cell:
a: 109.244Å b: 109.244Å c: 100.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.177 0.221
Expression system: Escherichia coli BL21(DE3)

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