› 4ruv

X-ray diffraction
1.93Å resolution

Crystal structure of thioredoxin 2 from Staphylococcus aureus NCTC8325

Released:
DOI: 10.2210/pdb4ruv/pdb
PDB entry 4ruv coloured by chain, front view.
PDB entry 4ruv coloured by chain, side view.
PDB entry 4ruv coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus NCTC 8325
Primary publication:
Elucidation of the mechanism of disulfide exchange between staphylococcal thioredoxin2 and thioredoxin reductase2: A structural insight.
Bose M, Bhattacharyya S, Biswas R, Roychowdhury A, Bhattacharjee A, Ghosh AK, Das AK
Biochimie 160 1-13 (2019)
PMID: 30710560

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 13.12 KDa
Source organism: Staphylococcus aureus subsp. aureus NCTC 8325
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2G000 (Residues: 1-106; Coverage: 100%)
Gene name: SAOUHSC_00834
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P41
Unit cell:
a: 31.376Å b: 31.376Å c: 94.804Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.17 0.239
Expression system: Escherichia coli

Quick links

Citations

2 mentions without citation

Quercetin conjugated with superparamagnetic iron oxide nanoparticles improves learning and memory better than free quercetin via interacting with proteins involved in LTP.
Amanzadeh et al. (2019)
1 more