› 4ttl

X-ray diffraction
1.7Å resolution

Racemic structure of cyclic Vc1.1 (cVc1.1-1)

Released:
DOI: 10.2210/pdb4ttl/pdb
PDB entry 4ttl coloured by chain, front view.
PDB entry 4ttl coloured by chain, side view.
PDB entry 4ttl coloured by chain, top view.
Source organism: Conus victoriae
Primary publication:
Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffolds.
Wang CK, King GJ, Northfield SE, Ojeda PG, Craik DJ
Angew Chem Int Ed Engl 53 11236-41 (2014)
PMID: 25168664

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-conotoxin Vc1a Chain: A
Molecule details ›
Chain: A
Length: 22 amino acids
Theoretical weight: 2.18 KDa
Source organism: Conus victoriae
Expression system: Not provided
UniProt:
  • Canonical: P69747 (Residues: 50-66; Coverage: 42%)
Sequence domains: Alpha conotoxin precursor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Unit cell:
a: 30.256Å b: 20.706Å c: 38.236Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.189 0.226
Expression system: Not provided

Quick links

Citations

7 citation in other articles

X-ray Crystallographic Structure of Oligomers Formed by a Toxic β-Hairpin Derived from α-Synuclein: Trimers and Higher-Order Oligomers.
Salveson et al. (2016)
6 more

2 mentions without citation

On the Utility of Chemical Strategies to Improve Peptide Gut Stability.
Kremsmayr et al. (2022)
1 more