› 4u92

X-ray diffraction
1.5Å resolution

Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad

Released:
DOI: 10.2210/pdb4u92/pdb
PDB entry 4u92 coloured by chain, front view.
PDB entry 4u92 coloured by chain, side view.
PDB entry 4u92 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad.
Zhang D, Huang T, Lukeman PS, Paukstelis PJ
Nucleic Acids Res 42 13422-9 (2014)
PMID: 25389267

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-118187 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*CP*AP*KP*GP*CP*GP*TP*GP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 2.79 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand BA 6 x BA
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P4
Unit cell:
a: 29.621Å b: 29.621Å c: 63.737Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.129 0.144
Expression system: Not provided

Quick links

Citations

17 citation in other articles

Quadruplex formation by both G-rich and C-rich DNA strands of the C9orf72 (GGGGCC)8•(GGCCCC)8 repeat: effect of CpG methylation.
Zamiri et al. (2015)
16 more

4 mentions without citation

Non-G Base Tetrads.
Escaja et al. (2022)
3 more