› 4w6v

X-ray diffraction
3.02Å resolution

Crystal structure of a peptide transporter from Yersinia enterocolitica at 3 A resolution

Released:
DOI: 10.2210/pdb4w6v/pdb
PDB entry 4w6v coloured by chain, front view.
PDB entry 4w6v coloured by chain, side view.
PDB entry 4w6v coloured by chain, top view.
Source organism: Yersinia enterocolitica subsp. palearctica YE-P4
Primary publication:
Role of electrostatic interactions for ligand recognition and specificity of peptide transporters.
Boggavarapu R, Jeckelmann JM, Harder D, Ucurum Z, Fotiadis D
BMC Biol 13 58 (2015)
PMID: 26246134

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide transporter YePEPT Chain: A
Molecule details ›
Chain: A
Length: 519 amino acids
Theoretical weight: 56.51 KDa
Source organism: Yersinia enterocolitica subsp. palearctica YE-P4
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A2R9TD79 (Residues: 1-511; Coverage: 100%)
Gene name: YEP4_02370
Sequence domains: POT family
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 90.656Å b: 101.041Å c: 104.175Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.259 0.257 0.294
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Understanding transport by the major facilitator superfamily (MFS): structures pave the way.
Quistgaard et al. (2016)
2 more

9 mentions without citation

Recent advances in understanding prodrug transport through the SLC15 family of proton-coupled transporters.
Minhas et al. (2020)
8 more