Function and Biology Details
Reaction catalysed:
5,6-dihydrouracil(20) in tRNA + NAD(P)(+) = uracil(20) in tRNA + NAD(P)H
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (preferred)
PDBe Complex ID:
PDB-CPX-192677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Molecule details ›
Chains: A, B, C
Length: 120 amino acids
Theoretical weight: 13.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain
Length: 120 amino acids
Theoretical weight: 13.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9NX74 (Residues: 338-450; Coverage: 23%)
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SOLEIL BEAMLINE PROXIMA 1
Spacegroup:
P43
Expression system: Escherichia coli BL21(DE3)
