› 4wh0

X-ray diffraction
2.56Å resolution

YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine

Released:
DOI: 10.2210/pdb4wh0/pdb
PDB entry 4wh0 coloured by chain, front view.
PDB entry 4wh0 coloured by chain, side view.
PDB entry 4wh0 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct.
Grøftehauge MK, Truan D, Vasil A, Denny PW, Vasil ML, Pohl E
Int J Mol Sci 16 15971-84 (2015)
PMID: 26184183

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191364 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isochorismatase-like domain-containing protein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 205 amino acids
Theoretical weight: 22.71 KDa
Source organism: Pseudomonas aeruginosa
UniProt:
  • Canonical: Q9I4D6 (Residues: 1-205; Coverage: 100%)
Gene name: PA1202
Sequence domains: Isochorismatase family
Structure domains: Isochorismatase-like

Ligands and Environments

1 bound ligand:
Ligand CL 8 x CL
2 modified residues:
Ligand MSE 32 x MSE
Ligand CSS 8 x CSS

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 74.46Å b: 114.53Å c: 96.16Å
α: 90° β: 91.9° γ: 90°
R-values:
R R work R free
0.148 0.146 0.191

Quick links

Citations

5 citation in other articles

RpoN/Sfa2-dependent activation of the Pseudomonas aeruginosa H2-T6SS and its cognate arsenal of antibacterial toxins.
Allsopp et al. (2022)
4 more

2 mentions without citation

Diverse architectural properties of Sso10a proteins: Evidence for a role in chromatin compaction and organization.
Driessen et al. (2016)
1 more