4wjl

X-ray diffraction
3.4Å resolution

Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-185413 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Inactive dipeptidyl peptidase 10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 719 amino acids
Theoretical weight: 82.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8N608 (Residues: 65-783; Coverage: 90%)
Gene names: DPP10, DPRP3, KIAA1492
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 80.91Å b: 143.73Å c: 176.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.207 0.242
Expression system: Spodoptera frugiperda