› 4wpd

X-ray diffraction
2Å resolution

X-ray Crystal Structure of CYP119 complexed with 4-(4-flourophenyl)-1H-imidazole

Released:
DOI: 10.2210/pdb4wpd/pdb
PDB entry 4wpd coloured by chain, front view.
PDB entry 4wpd coloured by chain, side view.
PDB entry 4wpd coloured by chain, top view.
Source organism: Sulfolobus acidocaldarius DSM 639
Entry author: Madrona Y

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176264 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome P450 119 Chains: A, B
Molecule details ›
Chains: A, B
Length: 368 amino acids
Theoretical weight: 42.92 KDa
Source organism: Sulfolobus acidocaldarius DSM 639
Expression system: Escherichia coli
UniProt:
  • Canonical: Q55080 (Residues: 1-368; Coverage: 100%)
Gene names: Saci_2081, cyp119
Sequence domains: Cytochrome P450
Structure domains: Cytochrome P450

Ligands and Environments


Cofactor: Ligand HEM 2 x HEM
1 bound ligand:
Ligand 3SQ 2 x 3SQ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 78.801Å b: 95.458Å c: 106.715Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.157 0.199
Expression system: Escherichia coli

Quick links