› 4wvv

X-ray diffraction
1.2Å resolution

Chicken Galectin-8 N-terminal domain complexed with lactose

Released:
DOI: 10.2210/pdb4wvv/pdb
PDB entry 4wvv coloured by chain, front view.
PDB entry 4wvv coloured by chain, side view.
PDB entry 4wvv coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Combining Crystallography and Hydrogen-Deuterium Exchange to Study Galectin-Ligand Complexes.
Ruiz FM, Gilles U, Lindner I, André S, Romero A, Reusch D, Gabius HJ
Chemistry 21 13558-68 (2015)
PMID: 26270612

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin Chain: A
Molecule details ›
Chain: A
Length: 145 amino acids
Theoretical weight: 16.64 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q1W2P6 (Residues: 9-153; Coverage: 49%)
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC, GAL
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P6122
Unit cell:
a: 56.459Å b: 56.459Å c: 201.239Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.153 0.152 0.166
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Sweet complementarity: the functional pairing of glycans with lectins.
Gabius et al. (2016)
1 more