› 4x0r

X-ray diffraction
2.9Å resolution

Crystal structure of human MxB stalk domain

Released:
DOI: 10.2210/pdb4x0r/pdb
PDB entry 4x0r coloured by chain, front view.
PDB entry 4x0r coloured by chain, side view.
PDB entry 4x0r coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insight into the assembly of human anti-HIV dynamin-like protein MxB/Mx2.
Xu B, Kong J, Wang X, Wei W, Xie W, Yu XF
Biochem Biophys Res Commun 456 197-201 (2015)
PMID: 25446123

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149013 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-induced GTP-binding protein Mx2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 239 amino acids
Theoretical weight: 28.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20592 (Residues: 413-679; Coverage: 33%)
Gene name: MX2
Sequence domains:
Structure domains: Dynamin, middle domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P3121
Unit cell:
a: 154.612Å b: 154.612Å c: 103.34Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.218 0.241
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Capsid-Dependent Host Factors in HIV-1 Infection.
Yamashita et al. (2017)
3 more