› 4x29

X-ray diffraction
2.4Å resolution

Structural basis for the enhancement of virulence by entomopoxvirus fusolin and its in vivo crystallization into viral spindles (complex with Zinc)

Released:
DOI: 10.2210/pdb4x29/pdb
PDB entry 4x29 coloured by chain, front view.
PDB entry 4x29 coloured by chain, side view.
PDB entry 4x29 coloured by chain, top view.
Source organism: Entomopoxvirinae
Primary publication:
Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization.
Chiu E, Hijnen M, Bunker RD, Boudes M, Rajendran C, Aizel K, Oliéric V, Schulze-Briese C, Mitsuhashi W, Young V, Ward VK, Bergoin M, Metcalf P, Coulibaly F
Proc Natl Acad Sci U S A 112 3973-8 (2015)
PMID: 25787255

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182783 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chitin-binding type-4 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 43.76 KDa
Source organism: Entomopoxvirinae
UniProt:
  • Canonical: Q83389 (Residues: 19-372, 373-386; Coverage: 95%)
Sequence domains: Lytic polysaccharide mono-oxygenase, cellulose-degrading

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P41212
Unit cell:
a: 71.79Å b: 71.79Å c: 129.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.156 0.223

Quick links

Citations

7 review citations

Enzymatic Modifications of Chitin, Chitosan, and Chitooligosaccharides.
Kaczmarek et al. (2019)
6 more

3 mentions without citation

Oxygen Activation by Cu LPMOs in Recalcitrant Carbohydrate Polysaccharide Conversion to Monomer Sugars.
Meier et al. (2018)
2 more