› 4x30

X-ray diffraction
1.55Å resolution

Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution

Released:
DOI: 10.2210/pdb4x30/pdb
PDB entry 4x30 coloured by chain, front view.
PDB entry 4x30 coloured by chain, side view.
PDB entry 4x30 coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Qi X

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138702 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thyroxine-binding globulin Chain: A
Molecule details ›
Chain: A
Length: 395 amino acids
Theoretical weight: 44.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05543 (Residues: 21-415; Coverage: 100%)
Gene names: SERPINA7, TBG
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand T44 1 x T44
Ligand GOL 2 x GOL
Ligand F 1 x F
Ligand EDO 1 x EDO
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43212
Unit cell:
a: 65.46Å b: 65.46Å c: 202.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.183 0.205
Expression system: Escherichia coli

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