› 4x5l

X-ray diffraction
2.37Å resolution

Crystal structure of Dscam1 Ig7 domain, isoform 9

Released:
DOI: 10.2210/pdb4x5l/pdb
Model geometry
Fit model/data
PDB entry 4x5l coloured by chain, front view.
PDB entry 4x5l coloured by chain, side view.
PDB entry 4x5l coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition.
Li SA, Cheng L, Yu Y, Wang JH, Chen Q
OpenAccess logo Sci Adv 2 e1501118 (2016)
PMID: 27386517

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192416 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell adhesion molecule Dscam1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 102 amino acids
Theoretical weight: 10.74 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0E9H9 (Residues: 616-712; Coverage: 5%)
Gene names: CG17800, Dscam, Dscam1, p270
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P222
Unit cell:
a: 45.527Å b: 117.37Å c: 117.333Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.215 0.247
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly.
Mountoufaris et al. (2018)
1 more

1 mention without citation

Structural basis for the self-recognition of sDSCAM in Chelicerata.
Cheng et al. (2023)