› 4x82

X-ray diffraction
2.76Å resolution

Crystal Structure of the Extracellular Domain of ZIP4

Released:
DOI: 10.2210/pdb4x82/pdb
PDB entry 4x82 coloured by chain, front view.
PDB entry 4x82 coloured by chain, side view.
PDB entry 4x82 coloured by chain, top view.
Source organism: Pteropus alecto
Primary publication:
Structural insights of ZIP4 extracellular domain critical for optimal zinc transport.
Zhang T, Sui D, Hu J
Nat Commun 7 11979 (2016)
PMID: 27321477

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125795 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc transporter ZIP4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 287 amino acids
Theoretical weight: 30.07 KDa
Source organism: Pteropus alecto
Expression system: Escherichia coli
UniProt:
  • Canonical: L5KLU7 (Residues: 36-322; Coverage: 47%)
Gene names: SLC39A4, ZIP4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 34.182Å b: 68.731Å c: 93.971Å
α: 90° β: 95.79° γ: 90°
R-values:
R R work R free
0.212 0.206 0.264
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis.
Hara et al. (2017)
14 more

4 mentions without citation

Structural insights of ZIP4 extracellular domain critical for optimal zinc transport.
Zhang et al. (2016)
3 more