4xcl

X-ray diffraction
1.21Å resolution

N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with AGS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-157069 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock cognate 90 kDa protein Chain: A
Molecule details ›
Chain: A
Length: 259 amino acids
Theoretical weight: 29.23 KDa
Source organism: Dictyostelium discoideum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54651 (Residues: 1-223; Coverage: 32%)
Gene names: DDB_G0267400, hsc90, hsp90, hspD
Sequence domains: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Structure domains: Histidine kinase-like ATPase, C-terminal domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 41.867Å b: 46.754Å c: 59.487Å
α: 90° β: 106.81° γ: 90°
R-values:
R R work R free
0.16 0.159 0.181
Expression system: Escherichia coli BL21(DE3)