Function and Biology Details
Reaction catalysed:
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD(P)(+) = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
Ketol-acid reductoisomerase (NAD(P)(+)) (preferred)
PDBe Complex ID:
PDB-CPX-122694 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ketol-acid reductoisomerase (NAD(P)(+))
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 38.47 KDa
Source organism: Ignisphaera aggregans DSM 17230
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 343 amino acids
Theoretical weight: 38.47 KDa
Source organism: Ignisphaera aggregans DSM 17230
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
E0SRA9 (Residues: 1-335; Coverage: 100%)
Sequence domains:
- Acetohydroxy acid isomeroreductase, NADPH-binding domain
- Ketol-acid reductoisomerase, C-terminal domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
SSRL BEAMLINE BL12-2
Expression system: Escherichia coli BL21(DE3)
