› 4xh3

X-ray diffraction
2.1Å resolution

Mechanistic insights into anchorage of the contractile ring from yeast to humans

Released:
DOI: 10.2210/pdb4xh3/pdb
PDB entry 4xh3 coloured by chain, front view.
PDB entry 4xh3 coloured by chain, side view.
PDB entry 4xh3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mechanistic insights into the anchorage of the contractile ring by anillin and Mid1.
Sun L, Guan R, Lee IJ, Liu Y, Chen M, Wang J, Wu JQ, Chen Z
Dev Cell 33 413-26 (2015)
PMID: 25959226

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192518 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anillin Chain: A
Molecule details ›
Chain: A
Length: 416 amino acids
Theoretical weight: 46.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NQW6 (Residues: 712-1124; Coverage: 37%)
Gene name: ANLN
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 90.148Å b: 126.116Å c: 54.132Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.218 0.248
Expression system: Escherichia coli

Quick links

Citations

23 review citations

Rho GTPases and actomyosin: Partners in regulating epithelial cell-cell junction structure and function.
Arnold et al. (2017)
22 more

2 mentions without citation

Mechanistic insights into the anchorage of the contractile ring by anillin and Mid1.
Sun et al. (2015)
1 more