Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158283 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neuroepithelial cell-transforming gene 1 protein
Molecule details ›
Chains: A, D
Length: 361 amino acids
Theoretical weight: 42.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli DH1
UniProt:
Sequence domains:
Length: 361 amino acids
Theoretical weight: 42.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli DH1
UniProt:
- Canonical:
Q7Z628 (Residues: 149-501; Coverage: 59%)
Sequence domains:
Transforming protein RhoA
Molecule details ›
Chains: B, E
Length: 180 amino acids
Theoretical weight: 20.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli DH1
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 180 amino acids
Theoretical weight: 20.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli DH1
UniProt:
- Canonical: P61586 (Residues: 2-180; Coverage: 93%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-1
Spacegroup:
P21
Expression system: Escherichia coli DH1
