› 4xhh

X-ray diffraction
2.91Å resolution

Structure of C. glabrata Hrr25, Apo state

Released:
DOI: 10.2210/pdb4xhh/pdb
PDB entry 4xhh coloured by chain, front view.
PDB entry 4xhh coloured by chain, side view.
PDB entry 4xhh coloured by chain, top view.
Source organism: [Candida] glabrata
Primary publication:
Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.
Ye Q, Ur SN, Su TY, Corbett KD
EMBO J 35 2139-2151 (2016)
PMID: 27491543

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
non-specific serine/threonine protein kinase Chain: A
Molecule details ›
Chain: A
Length: 403 amino acids
Theoretical weight: 46.75 KDa
Source organism: [Candida] glabrata
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6FS46 (Residues: 1-403; Coverage: 81%)
Gene name: CAGL0H03553g
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:
Ligand PO4 7 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Unit cell:
a: 72.091Å b: 77.86Å c: 85.078Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.203 0.225
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).
Xu et al. (2019)
4 more