› 4xno

X-ray diffraction
1.98Å resolution

Crystal structure of 5'-CTTATPPPZZZATAAG

Released:
DOI: 10.2210/pdb4xno/pdb
PDB entry 4xno coloured by chain, front view.
PDB entry 4xno coloured by chain, side view.
PDB entry 4xno coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Structural basis for a six nucleotide genetic alphabet.
Georgiadis MM, Singh I, Kellett WF, Hoshika S, Benner SA, Richards NG
J Am Chem Soc 137 6947-55 (2015)
PMID: 25961938

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-118271 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*TP*(BRU)P*AP*TP*(1WA)P*(1WA)P*(1WA)P*(1W5)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 16 nucleotides
Theoretical weight: 5.1 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand BRU 2 x BRU

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3221
Unit cell:
a: 42.019Å b: 42.019Å c: 140.472Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.212 0.238
Expression system: Not provided

Quick links

Citations

16 review citations

Generation of Aptamers with an Expanded Chemical Repertoire.
Diafa et al. (2015)
15 more

6 mentions without citation

Structural basis for a six nucleotide genetic alphabet.
Georgiadis et al. (2015)
5 more