› 4xrk

X-ray diffraction
3.25Å resolution

Crystal Structure of Importin Beta in a Polyethylene Glycol Condition

Released:
DOI: 10.2210/pdb4xrk/pdb
Model geometry
Fit model/data
PDB entry 4xrk coloured by chain, front view.
PDB entry 4xrk coloured by chain, side view.
PDB entry 4xrk coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Impact of the crystallization condition on importin-β conformation.
Tauchert MJ, Hémonnot C, Neumann P, Köster S, Ficner R, Dickmanns A
Acta Crystallogr D Struct Biol 72 705-17 (2016)
PMID: 27303791

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123958 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Importin N-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 882 amino acids
Theoretical weight: 96.65 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0S143 (Residues: 1-877; Coverage: 100%)
Gene name: CTHT_0012280
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Unit cell:
a: 64.41Å b: 121.19Å c: 132.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.291 0.29 0.317
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Identifying and Visualizing Macromolecular Flexibility in Structural Biology.
Palamini et al. (2016)
4 other articles

1 mention without citation

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.
Atkinson et al. (2018)