› 4xuw

X-ray diffraction
1.1Å resolution

Structure of the hazelnut allergen, Cor a 8

Released:
DOI: 10.2210/pdb4xuw/pdb
PDB entry 4xuw coloured by chain, front view.
PDB entry 4xuw coloured by chain, side view.
PDB entry 4xuw coloured by chain, top view.
Source organism: Corylus avellana
Primary publication:
Structural and Functional Characterization of the Hazelnut Allergen Cor a 8.
Offermann LR, Bublin M, Perdue ML, Pfeifer S, Dubiela P, Borowski T, Chruszcz M, Hoffmann-Sommergruber K
J Agric Food Chem 63 9150-8 (2015)
PMID: 26417906

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189606 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-specific lipid-transfer protein Cor a 8.0101 Chains: A, B
Molecule details ›
Chains: A, B
Length: 92 amino acids
Theoretical weight: 9.49 KDa
Source organism: Corylus avellana
UniProt:
  • Canonical: Q9ATH2 (Residues: 24-115; Coverage: 100%)
Sequence domains: Protease inhibitor/seed storage/LTP family
Structure domains: Plant lipid-transfer and hydrophobic proteins

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P21
Unit cell:
a: 39.678Å b: 30.816Å c: 56.184Å
α: 90° β: 108.91° γ: 90°
R-values:
R R work R free
0.144 0.142 0.177

Quick links

Citations

4 review citations

Factors and co-factors influencing clinical manifestations in nsLTPs allergy: between the good and the bad.
Ridolo et al. (2023)
3 more

4 mentions without citation

Lipid transfer proteins: classification, nomenclature, structure, and function.
Salminen et al. (2016)
3 more