› 4ybq

X-ray diffraction
3.27Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-235094 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Solute carrier family 2, facilitated glucose transporter member 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 508 amino acids
Theoretical weight: 56.43 KDa
Source organism: Rattus norvegicus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P43427 (Residues: 1-502; Coverage: 100%)
Gene names: Glut5, Slc2a5
Sequence domains: Sugar (and other) transporter
Structure domains: MFS general substrate transporter like domains
antibody Fv fragment light chain Chains: C, E
Molecule details ›
Chains: C, E
Length: 122 amino acids
Theoretical weight: 13.45 KDa
Source organism: Mus musculus
Expression system: Brevibacillus choshinensis
Structure domains: Immunoglobulins
antibody Fv fragment heavy chain Chains: D, F
Molecule details ›
Chains: D, F
Length: 136 amino acids
Theoretical weight: 14.86 KDa
Source organism: Mus musculus
Expression system: Brevibacillus choshinensis
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21
Unit cell:
a: 76.773Å b: 151.541Å c: 106.396Å
α: 90° β: 97.25° γ: 90°
R-values:
R R work R free
0.244 0.242 0.288
Expression systems:
  • Saccharomyces cerevisiae
  • Brevibacillus choshinensis

Quick links

Citations

30 review citations

Shared Molecular Mechanisms of Membrane Transporters.
Drew et al. (2016)
29 more

32 mentions without citation

GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters.
Deng et al. (2016)
31 more