› 4ybr

X-ray diffraction
1.65Å resolution

Structure of Mycobacterium tuberculosis NadD in complex with NADP, P21212

Released:
DOI: 10.2210/pdb4ybr/pdb
PDB entry 4ybr coloured by chain, front view.
PDB entry 4ybr coloured by chain, side view.
PDB entry 4ybr coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry author: Korotkov KV

Function and Biology Details

Reaction catalysed: 
ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD(+)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161693 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable nicotinate-nucleotide adenylyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 201 amino acids
Theoretical weight: 22.35 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WJJ5 (Residues: 1-195; Coverage: 91%)
Gene names: MTCY428.26, Rv2421c, nadD
Sequence domains: Cytidylyltransferase-like
Structure domains: HUPs

Ligands and Environments

4 bound ligands:
Ligand NAP 2 x NAP
Ligand EPE 2 x EPE
Ligand SO4 2 x SO4
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21212
Unit cell:
a: 49.04Å b: 141.43Å c: 63.17Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.19 0.216
Expression system: Escherichia coli

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