› 4yd8

X-ray diffraction
1.8Å resolution

Bardet-Biedl Syndrome 9 Protein (aa1-407), Homo sapiens

Released:
DOI: 10.2210/pdb4yd8/pdb
PDB entry 4yd8 coloured by chain, front view.
PDB entry 4yd8 coloured by chain, side view.
PDB entry 4yd8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural Characterization of Bardet-Biedl Syndrome 9 Protein (BBS9).
Knockenhauer KE, Schwartz TU
J Biol Chem 290 19569-83 (2015)
PMID: 26085087

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174790 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein PTHB1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 411 amino acids
Theoretical weight: 46.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q3SYG4 (Residues: 1-407; Coverage: 46%)
Gene names: BBS9, PTHB1
Sequence domains: PTHB1 N-terminus

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 26 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21212
Unit cell:
a: 136.417Å b: 81.878Å c: 85.649Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.169 0.2
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Trafficking of ciliary membrane proteins by the intraflagellar transport/BBSome machinery.
Wingfield et al. (2018)
1 more

5 mentions without citation

Structural Characterization of Bardet-Biedl Syndrome 9 Protein (BBS9).
Knockenhauer et al. (2015)
4 more