Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189267 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cerebral cavernous malformations 2 protein
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 11.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Cerebral cavernous malformation protein, harmonin-homology
Structure domains: Paired amphipathic helix 2 (pah2 repeat)
Length: 96 amino acids
Theoretical weight: 11.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9BSQ5 (Residues: 290-376; Coverage: 20%)
Sequence domains: Cerebral cavernous malformation protein, harmonin-homology
Structure domains: Paired amphipathic helix 2 (pah2 repeat)
Mitogen-activated protein kinase kinase kinase 3
Molecule details ›
Chain: B
Length: 22 amino acids
Theoretical weight: 2.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 22 amino acids
Theoretical weight: 2.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q99759 (Residues: 1-22; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU FR-E SUPERBRIGHT
Spacegroup:
P43212
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
