› 4yrh

X-ray diffraction
2.86Å resolution

p21 isoform of MEC-17 from Danio Rerio

Released:
DOI: 10.2210/pdb4yrh/pdb
PDB entry 4yrh coloured by chain, front view.
PDB entry 4yrh coloured by chain, side view.
PDB entry 4yrh coloured by chain, top view.
Source organism: Danio rerio
Entry author: Xue T

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + [alpha-tubulin]-L-lysine = CoA + [alpha-tubulin]-N(6)-acetyl-L-lysine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180153 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-tubulin N-acetyltransferase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 184 amino acids
Theoretical weight: 20.89 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PH17 (Residues: 2-185; Coverage: 62%)
Gene names: atat1, mec17, si:ch211-152p11.5, zgc:65893
Sequence domains: GNAT acetyltransferase, Mec-17
Structure domains: Aminopeptidase

Ligands and Environments


Cofactor: Ligand ACO 2 x ACO
1 bound ligand:
Ligand EPE 2 x EPE
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 74.374Å b: 66.299Å c: 75.841Å
α: 90° β: 103.84° γ: 90°
R-values:
R R work R free
0.221 0.218 0.256
Expression system: Escherichia coli

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