4yyl

X-ray diffraction
1.9Å resolution

Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-137016 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase acidic protein Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 22.3 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Escherichia coli
UniProt:
  • Canonical: P03433 (Residues: 1-50, 73-197; Coverage: 24%)
Gene name: PA
Structure domains: Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P41212
Unit cell:
a: 66.766Å b: 66.766Å c: 126.251Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.234
Expression system: Escherichia coli