› 4z0o

X-ray diffraction
1.57Å resolution

CW-type zinc finger of ZCWPW2 with F78D mutation

Released:
DOI: 10.2210/pdb4z0o/pdb
PDB entry 4z0o coloured by chain, front view.
PDB entry 4z0o coloured by chain, side view.
PDB entry 4z0o coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Liu Y, Tempel W, Bountra C, Arrowsmith CH, Edwards AM, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175879 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger CW-type PWWP domain protein 2 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 7.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q504Y3 (Residues: 21-78; Coverage: 16%)
Gene name: ZCWPW2
Sequence domains: CW-type Zinc Finger
Structure domains: Herpes Virus-1

Ligands and Environments

3 bound ligands:
Ligand ZN 1 x ZN
Ligand NA 1 x NA
Ligand UNX 9 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P321
Unit cell:
a: 47.569Å b: 47.569Å c: 48.96Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.164 0.186
Expression system: Escherichia coli BL21(DE3)

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