› 4z8j

X-ray diffraction
0.95Å resolution

Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif

Released:
DOI: 10.2210/pdb4z8j/pdb
PDB entry 4z8j coloured by chain, front view.
PDB entry 4z8j coloured by chain, side view.
PDB entry 4z8j coloured by chain, top view.
Source organisms:
Entry authors: Clairfeuille T, Pavlos N, Collins BM

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169891 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Sorting nexin-27 Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 10.57 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8K4V4 (Residues: 39-133; Coverage: 18%)
Gene names: Mrt1, Snx27
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Parathyroid hormone/parathyroid hormone-related peptide receptor Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q03431 (Residues: 586-593; Coverage: 1%)
Gene names: PTH1R, PTHR, PTHR1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 37.07Å b: 48.625Å c: 55.725Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.144 0.144 0.144
Expression systems:
  • Escherichia coli
  • Not provided

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