› 4zb8

X-ray diffraction
2Å resolution

Crystal structure of the glutathione transferase URE2P6 from Phanerochaete chrysosporium in complex with oxidized glutathione.

Released:
DOI: 10.2210/pdb4zb8/pdb
PDB entry 4zb8 coloured by chain, front view.
PDB entry 4zb8 coloured by chain, side view.
PDB entry 4zb8 coloured by chain, top view.
Source organism: Phanerodontia chrysosporium
Primary publication:
Evolutionary divergence of Ure2pA glutathione transferases in wood degrading fungi.
Roret T, Thuillier A, Favier F, Gelhaye E, Didierjean C, Morel-Rouhier M
Fungal Genet Biol 83 103-112 (2015)
PMID: 26348000

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102633 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.57 KDa
Source organism: Phanerodontia chrysosporium
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0R4I981 (Residues: 1-222; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand GDS 1 x GDS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: C2221
Unit cell:
a: 70.848Å b: 77.378Å c: 89.212Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.192 0.21
Expression system: Escherichia coli

Quick links

Citations

11 citation in other articles

Conserved white-rot enzymatic mechanism for wood decay in the Basidiomycota genus Pycnoporus.
Miyauchi et al. (2020)
10 more

1 mention without citation

Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Scherlach et al. (2021)