› 4zka

X-ray diffraction
1.8Å resolution

High Resolution Crystal Structure of Fox1 RRM

Released:
DOI: 10.2210/pdb4zka/pdb
PDB entry 4zka coloured by chain, front view.
PDB entry 4zka coloured by chain, side view.
PDB entry 4zka coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Blatter M, Allain FH-T

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192649 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA binding protein fox-1 homolog 1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 100 amino acids
Theoretical weight: 11.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NWB1 (Residues: 109-208; Coverage: 25%)
Gene names: A2BP, A2BP1, FOX1, HRNBP1, RBFOX1
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

3 bound ligands:
Ligand SO4 7 x SO4
Ligand MES 4 x MES
Ligand PG4 1 x PG4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 68.98Å b: 77.617Å c: 106.386Å
α: 90° β: 93.99° γ: 90°
R-values:
R R work R free
0.195 0.194 0.226
Expression system: Escherichia coli BL21(DE3)

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