› 4zkq

X-ray diffraction
1.9Å resolution

Viral chemokine binding protein R17 encoded by rodent gammaherpesvirus Peru ( RHVP)

Released:
DOI: 10.2210/pdb4zkq/pdb
PDB entry 4zkq coloured by chain, front view.
PDB entry 4zkq coloured by chain, side view.
PDB entry 4zkq coloured by chain, top view.
Source organism: Cricetid gammaherpesvirus 2
Primary publication:
Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Lubman OY, Fremont DH
Structure 24 57-69 (2016)
PMID: 26671708

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123180 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Putative uncharacterized protein Chain: A
Molecule details ›
Chain: A
Length: 420 amino acids
Theoretical weight: 47.47 KDa
Source organism: Cricetid gammaherpesvirus 2
Expression system: Mammalian expression vector pBGSA
UniProt:
  • Canonical: E9M5R0 (Residues: 28-439; Coverage: 94%)
Gene names: RHVP-L.R17, RHVP.R17

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 69.561Å b: 75.835Å c: 106.985Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.184 0.221
Expression system: Mammalian expression vector pBGSA

Quick links

Citations

5 review citations

Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures.
Felix et al. (2017)
4 more

2 mentions without citation

The binding and specificity of chemokine binding proteins, through the lens of experiment and computation.
Stark et al. (2022)
1 more