Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Roquin-2 (preferred)
PDBe Complex ID:
PDB-CPX-190743 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Roquin-2
Molecule details ›
Chains: A, B, C, D
Length: 155 amino acids
Theoretical weight: 17.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)
Length: 155 amino acids
Theoretical weight: 17.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9HBD1 (Residues: 171-325; Coverage: 13%)
Sequence domains:
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL41XU
Spacegroup:
P212121
Expression system: Escherichia coli
