› 4zxn

X-ray diffraction
2.2Å resolution

Crystal structure of rat coronavirus strain New-Jersey Hemagglutinin-Esterase

Released:
DOI: 10.2210/pdb4zxn/pdb
PDB entry 4zxn coloured by chain, front view.
PDB entry 4zxn coloured by chain, side view.
PDB entry 4zxn coloured by chain, top view.
Source organism: Rat coronavirus (strain NJ)
Entry authors: Bakkers MJG, Feitsma LJ, Huizinga EG, de Groot RJ

Function and Biology Details

Reaction catalysed: 
N-acetyl-O-acetylneuraminate + H(2)O = N-acetylneuraminate + acetate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174562 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin-esterase Chain: A
Molecule details ›
Chain: A
Length: 388 amino acids
Theoretical weight: 43.61 KDa
Source organism: Rat coronavirus (strain NJ)
Expression system: Homo sapiens
UniProt:
  • Canonical: Q3HS77 (Residues: 22-400; Coverage: 87%)
Gene name: HE
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand NAG 6 x NAG
Ligand NA 1 x NA
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2221
Unit cell:
a: 60.71Å b: 184.37Å c: 76.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.232 0.278
Expression system: Homo sapiens

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