› 4zy8

X-ray diffraction
2.14Å resolution

K. lactis Lst4 longin domain

Released:
DOI: 10.2210/pdb4zy8/pdb
PDB entry 4zy8 coloured by chain, front view.
PDB entry 4zy8 coloured by chain, side view.
PDB entry 4zy8 coloured by chain, top view.
Source organism: Kluyveromyces lactis
Primary publication:
Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein.
Pacitto A, Ascher DB, Wong LH, Blaszczyk BK, Nookala RK, Zhang N, Dokudovskaya S, Levine TP, Blundell TL
Open Biol 5 150174 (2015)
PMID: 26631379

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179474 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein LST4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 181 amino acids
Theoretical weight: 20.64 KDa
Source organism: Kluyveromyces lactis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6CXP4 (Residues: 56-56, 58-226; Coverage: 24%)
Gene names: KLLA0A06622g, LST4
Sequence domains: Yeast longin domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P42212
Unit cell:
a: 120.703Å b: 120.703Å c: 93.285Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.211 0.252
Expression system: Escherichia coli

Quick links

Citations

4 review citations

FLCN: The causative gene for Birt-Hogg-Dubé syndrome.
Schmidt et al. (2018)
3 more

3 mentions without citation

Nutrient Signaling and Lysosome Positioning Crosstalk Through a Multifunctional Protein, Folliculin.
de Martín Garrido et al. (2020)
2 more